Born in 1896 in Talasserry, Malabar in the erstwhile Madras Province (now in Kannur District, Kerala). The four storey building where he was born is still in good shape at Wadhyar Peedika, Thalassery. His father was Haji Ishaq Haji Ayub Sait and mother Fathima Bai. He married Asia Bai, daughter of Abdul Sattar Omar Hashmani of Thiruvananthapuram. (Step sister of Abdul Rahman Abdul Sathar Sait and Joonus Abdul Sathar Sait) Asia Bai died without any issues and he then married Halima Bai of Bangalore, who was reportedly assasinated by burglers in the early 1980s, while in Karachi.. Haji Abdul Sathar Sait was a prominent political figure in India and was the President of Muslim League in Malabar. He was elected member of the Constituent Assembly of India from the Madras Presidency. Even after the declaration of partition he continued to attend the  Constitutent Assembly. It is on record that he did actively participate in its meeting on 14th July 1947. At this meeting the first name to be called by the Secretary, asking members to sign the attendance register was that of Haji Abdul Sathar Haji Ishaq Sait. A point of order was raised by Deshbandhu Gupta that the member should be asked "whether he still subscribes to the Two-Nation theory or not? I take it that, as a sovereign body, and in view of the Partition that has been decided upon, we should review the whole question and lay down that a Member who does not subscribe to the Objectives Resolution that has been passed cannot sign the Register." The President, Dr. Rajendra Prasad gave the ruling  "An interesting point has been raised. But I do not consider it is a point of order at all. It is a question of the right of Members who have been elected to the Constituent Assembly under the procedure laid clown. Any one who has been elected is entitled to sit in this House as long as he does not resign. Therefore I do not think I can prevent any Member who has been elected duly from signing the Register."(See Proceedings of the Constitution Assembly of India, Volume IV)